HOTSPOT
Your company help desk uses System Center 2012 Service Manager to manage and track problems.
You need to ensure that the manager of the help desk is notified automatically when a high-priority incident is
updated.
What should you configure? To answer, select the appropriate configuration in the answer area.
Hot Area:
Answer: 
Explanation:
Service Manager uses notification subscriptions to automatically send notifications to selected recipients when
a selected condition occurs.
Source: System Center 2012 Service Manager Console
My opinion it would be the Subscriptions menu as it gives access to the ‘Notification Subscription’ wizard.
http://technet.microsoft.com/en-us/library/ff460891.aspx
Before notifications are sent, first configure each notification channel, such as the settings for Simple Mail
Transfer Protocol (SMTP). Notification messages are sent based on a notification template. Therefore, you will
need to create a notification template. You can then use the Notification Subscription wizard to subscribe agroup of users to a notification that will be sent whenever the changes that you specify occur. Finally, you can
verify that a notification is sent by manually generating the change.
http://technet.microsoft.com/en-us/library/hh524284.aspx
– To create an email notification template and subscription – Step 4:
4. In the Administration pane, click Notifications, and then click Subscriptions. In the Tasks pane, click Create
Subscription, and then complete the Create E-Mail Notification Subscription Wizard.